Ketoconazole Cream 2% 20gm Antifungal Aluminium tube 1 TUBE / BOX

 Ketoconazole Cream 2% 20gm

COMPOSITION:

Each tube 20gm contains:Ketoconazole 200MG

PHARMACOLOGICAL ACTION:

Ketoconazole, a synthetic imidazole dioxolane, has an antimycotic activity against dermatophytes such as Trichophyton spp., Epidermophytonfloccosum and Microsporum spp.and against yeasts.

Ketoconazole does not produce detectable blood levels after topical application.

INDICATIONS:

Ketoconazole is indicated for topical application in the treatment of dermatophyte infections of the skin: tinea corporis, tinea cruris, tinea manus and tinea pedis due to Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis and Epidermophyton floccosum, as well as in the treatment of cutaneous candidiasis and tinea (pityriasis) versicolor.

CONTRA-INDICATIONS:

Ketoconazole is contra-indicated in individuals who have shown hypersensitivity to any of its ingredients.

DOSAGE AND DIRECTIONS FOR USE:
Ketoconazole should be applied to affected areas once daily. Treatment should be continued for a sufficient period, at least until a few days after disappearance of all symptoms. The diagnosis and/or treatment should

be reconsidered if no clinical improvement is noted after 4 weeks of therapy. General measures in regard to hygiene should be observed to control sources of infection or re-infection.
The usual duration of treatment is: tinea versicolor (2 - 3 weeks), yeast infections (2 - 3 weeks), tinea cruris

(2 - 4 weeks), tinea corporis (3 - 4 weeks), tinea pedis (4 - 6 weeks).

SIDE EFFECTS AND SPECIAL PRECAUTIONS:

Side-effects
Pruritus, irritation, and burning sensation have been reported during treatment with Ketoconazole. Also, in

rare circumstances, allergic local skin phenomena, such as contact dermatitis, have been associated with Ketoconazole cream or one of its components, namely sodium sulphite or propylene glycol.
Precautions:
Irritation may occur when Ketoconazole is used immediately after prolonged treatment with topical corticosteroids. Therefore, to prevent a rebound effect after stopping a prolonged treatment with topical corticosteroids, it is recommended to continue applying a mild topical corticosteroid in the morning and to apply Ketoconazole in the evening, and to subsequently and gradually withdraw the steroid therapy over a period of 2 - 3 weeks.
Pregnancy:
The safety in pregnancy and lactation has not been established.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:

Excessive topical application may lead to erythema, oedema and a burning sensation.

STORAGE INSTRUCTIONS:
Store in a cool and dry place between15-30.
KEEP OUT OF REACH OF CHILDREN.