Chloroquine Phosphate Tablets 100MG Anti malaria Medicine 10*20's / Box

Chloroquine Phosphate Tablets Anti malarial 100MG

COMPOSITION:

Each tablet contains:Chloroquine Phosphate 100MG.

PHARMACOLOGICAL ACTION:
 Chloroquine Phosphate is an anti-malarial agent with rapidly acting blood schizonticidal and some gametocyticidal activity. It is not effective against exoerythrocytic tissue stages of plasmodia.

INDICATIONS:

Malaria prophylaxis in areas where chloroquine resistance is not encountered. Treatment of malaria where clinical symptoms and parasitaemia are rapidly controlled provided that the patient did not contract malaria in a chloroquine-resistant area and was not using chloroquine as prophlaxis for malaria.

CONTRA-INDICATIONS:

Hypersensitivity to chloroquine.

WARNINGS
Plasmoquine should only be used during pregnancy if unavoidable and if the risk of malaria is more hazardous than the potential damage of chloroquine to the fetus. Chloroquine may temporarily affect visual accommodation and patients undergoing treatment should not take charge of vehicles or machinery until the effect of treatment is evident.
Long-term, large-dose therapy may cause ocular disturbances (damage to eyesight) and for this reason opthalmological examinations are recommended every 3 to 6 months during treatment.
Care is necessary in administering chloroquine to patients with impaired liver or renal function or with porphyria or psoriasis. Chloroquine should be used with extreme caution in epileptic patients as chloroquine may interfere with seizure control. Resistance of Plasmodium falciparum to chloroquine may develop.

DOSAGE AND DIRECTIONS FOR USE:

The dosages for children 6 - 12 years for malaria prevention and treatment, must be carefully calculated according to body-mass as indicated.

MALARIA PREVENTION:
ADULTS AND CHILDREN OVER 12 YEARS
2 tablets per week.
GENERAL GUIDELINE FOR CHILDREN 6 - 12 YEARS
1 tablet per week.
It is advisable to start taking PLASMOQUINE one or two weeks before entering a malaria area. Thereafter repeat dosage at strictly adhered to weekly intervals during exposure to risk and for four to six weeks after exposure. The medication should be taken on the same day of each week.
MALARIA TREATMENT:
ADULTS AND CHILDREN OVER 12 YEARS
4 tablets taken as a single dose followed by 2 tablets six hours later and then 2 tablets daily for the following two days.
Recommended paediatric dose: 10 mg base per kg body-mass, followed by 5 mg per kg after 6 hours, then 5 mg per kg daily for 2 days.
GENERAL GUIDELINE FOR CHILDREN 6 - 12 YEARS
2 tablets taken as a single dose followed by 1 tablet six hours later and then 1 tablet daily for the following two days.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Side effects occurring with antimalarial doses are usually reversible upon withdrawal of the medicine and include headache, gastro-intestinal disturbances such as nausea, vomiting and diarrhoea, pruritus and skin eruptions. Less frequently a range of mental changes have been reported, including psychotic episodes, anxiety and personality changes.
Prolonged treatment with high doses may lead to visual disturbances such as blurred vision and difficulty in focusing caused by corneal and retinal changes. Corneal opacities are normally reversible upon withdrawal of treatment whereas retinal changes resulting in severe visual impairment, may progress after discontinuation of treatment and are generally irreversible.

STORAGE INSTRUCTIONS:

Store below 25°C.
Protect from light.
Keep out of reach of children.